Society of African Journal Editors

Middle East African Journal of Ophthalmology

Visual hallucinations (Charles Bonnet syndrome) associated with neurosarcoidosis

Authors: Jason Zhang, Emily Waisbren, Nafiseh Hashemi, Andrew G Lee

Journal: Middle East African Journal of Ophthalmology

The Charles Bonnet syndrome (CBS) refers to lucid and complex visual hallucinations in cognitively normal patients with acquired vision loss. It can be associated with any type of vision loss including that related to macular degeneration, corneal disease, diabetic retinopathy, and occipital infarct. Neurosarcoidosis, a multi-systemic inflammatory granulomatous disease affecting both the central and peripheral nervous systems, is rarely associated with CBS. We report a patient with biopsy-confirmed neurosarcoidosis who experienced visual hallucinations following the development of a right seventh-nerve palsy, right facial paresthesia, and bilateral progressive visual loss. This case highlights the importance of recognizing that the CBS can occur in visual loss of any etiology.